The genomic landscape of ANCA-associated vasculitis: Distinct transcriptional signatures, molecular endotypes and comparison with systemic lupus erythematosus

The genomic landscape of ANCA-associated vasculitis: Distinct transcriptional signatures, molecular endotypes and comparison with systemic lupus erythematosus

IntroductionAnti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) present with a complex phenotype and are associated with high mortality and multi-organ involvement. We sought to define the transcriptional landscape and molecular endotypes of AAVs and compare it to systemic lup...

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Bibliographic Details
Main Authors: Aggelos Banos, Konstantinos Thomas, Panagiotis Garantziotis, Anastasia Filia, Nikolaos Malissovas, Antigone Pieta, Dimitrios Nikolakis, Alexandros G. Panagiotopoulos, Aglaia Chalkia, Dimitrios Petras, George Bertsias, Dimitrios T. Boumpas, Dimitrios Vassilopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
autoimmune diseases
vasculitis
lupus (SLE)
transcriptomics (RNA-seq)
endotypes of disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1072598/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1072598/full

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