Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain

Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain

Abstract Background 5-Hydroxymethylcytosine (5hmC) is an oxidation product of 5-methylcytosine (5mC), and adjacent CpG sites in mammalian genome can be co-methylated and co-hydroxymethylated due to the processivity of DNMT and TET enzymes. Results We applied TAB-seq and oxBS-seq to selectively detec...

Descripció completa

Dades bibliogràfiques
Autors principals: Qin Ma, Zhengzheng Xu, Huan Lu, Ziying Xu, Yuanyuan Zhou, Bifeng Yuan, Weimin Ci
Format: Article
Idioma:English
Publicat: BMC 2018-12-01
Col·lecció:Epigenetics & Chromatin
Matèries:
5hmC
5mC
Methylation haplotype block
Methylation haplotype load
Hydroxymethylation haplotype block
Accés en línia:http://link.springer.com/article/10.1186/s13072-018-0248-3

Internet

http://link.springer.com/article/10.1186/s13072-018-0248-3

Ítems similars