Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain
Abstract Background 5-Hydroxymethylcytosine (5hmC) is an oxidation product of 5-methylcytosine (5mC), and adjacent CpG sites in mammalian genome can be co-methylated and co-hydroxymethylated due to the processivity of DNMT and TET enzymes. Results We applied TAB-seq and oxBS-seq to selectively detec...
| Hauptverfasser: | , , , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
BMC
2018-12-01
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| Schriftenreihe: | Epigenetics & Chromatin |
| Schlagworte: | |
| Online Zugang: | http://link.springer.com/article/10.1186/s13072-018-0248-3 |