Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain
Abstract Background 5-Hydroxymethylcytosine (5hmC) is an oxidation product of 5-methylcytosine (5mC), and adjacent CpG sites in mammalian genome can be co-methylated and co-hydroxymethylated due to the processivity of DNMT and TET enzymes. Results We applied TAB-seq and oxBS-seq to selectively detec...
| Autori principali: | , , , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
BMC
2018-12-01
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| Serie: | Epigenetics & Chromatin |
| Soggetti: | |
| Accesso online: | http://link.springer.com/article/10.1186/s13072-018-0248-3 |