NF-L in cerebrospinal fluid and serum is a biomarker of neuronal damage in an inducible mouse model of neurodegeneration

NF-L in cerebrospinal fluid and serum is a biomarker of neuronal damage in an inducible mouse model of neurodegeneration

Accumulation of neurofilaments (NFs), the major constituents of the neuronal cytoskeleton, is a distinctive feature of neurological diseases and several studies have shown that soluble NFs can be detected in the cerebrospinal fluid (CSF) of patients with neurological diseases, such as multiple scler...

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Bibliographic Details
Main Authors: Anthony Brureau, Véronique Blanchard-Bregeon, Catherine Pech, Stéphanie Hamon, Pascal Chaillou, Jean-Claude Guillemot, Pascal Barneoud, Philippe Bertrand, Laurent Pradier, Thomas Rooney, Nathalie Schussler
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Neurobiology of Disease
Subjects:
Biomarker
Neurodegeneration
Neurofilament light chain
Cerebrospinal fluid
Inducible p25 mice
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117300815

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http://www.sciencedirect.com/science/article/pii/S0969996117300815

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