Obese Adipose Tissue Secretion Induces Inflammation in Preadipocytes: Role of Toll-Like Receptor-4

Obese Adipose Tissue Secretion Induces Inflammation in Preadipocytes: Role of Toll-Like Receptor-4

In obesity, the dysfunctional adipose tissue (AT) releases increased levels of proinflammatory adipokines such as TNFα, IL-6, and IL-1β and free fatty acids (FFAs), characterizing a chronic, low-grade inflammation. Whilst FFAs and proinflammatory adipokines are known to elicit an inflammatory respon...

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Bibliographic Details
Main Authors: Mariana Renovato-Martins, Catharina Moreira-Nunes, Georgia C. Atella, Christina Barja-Fidalgo, João Alfredo de Moraes
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Nutrients
Subjects:
adipose tissue
preadipocyte
TLR4
inflammation
free fatty acid
obesity
Online Access:https://www.mdpi.com/2072-6643/12/9/2828

Internet

https://www.mdpi.com/2072-6643/12/9/2828

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