Methamphetamine Increases the Proportion of SIV-Infected Microglia/Macrophages, Alters Metabolic Pathways, and Elevates Cell Death Pathways: A Single-Cell Analysis

Methamphetamine Increases the Proportion of SIV-Infected Microglia/Macrophages, Alters Metabolic Pathways, and Elevates Cell Death Pathways: A Single-Cell Analysis

Both substance use disorder and HIV infection continue to affect many individuals. Both have untoward effects on the brain, and the two conditions often co-exist. In the brain, macrophages and microglia are infectable by HIV, and these cells are also targets for the effects of drugs of abuse, such a...

Full description

Bibliographic Details
Main Authors: Meng Niu, Brenda Morsey, Benjamin G. Lamberty, Katy Emanuel, Fang Yu, Rosiris León-Rivera, Joan W. Berman, Peter J. Gaskill, Stephanie M. Matt, Pawel S. Ciborowski, Howard S. Fox
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Viruses
Subjects:
HIV
SIV
neuroHIV
HIV-associated neurocognitive disorders (HAND)
macrophage
microglia
Online Access:https://www.mdpi.com/1999-4915/12/11/1297

Internet

https://www.mdpi.com/1999-4915/12/11/1297

Similar Items