Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations

Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations

Toxicological studies are a part of the drug development process and the preclinical stages, for which suitable vehicles ensuring easy and safe administration are crucial. However, poor aqueous solubility of drugs complicates vehicle screening for oral administration since non-aqueous solvents are o...

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Bibliographic Details
Main Authors: Tim Becker, Jan Heitkötter, Anna K. Krome, Andrea Schiefer, Kenneth Pfarr, Alexandra Ehrens, Miriam Grosse, Birthe Sandargo, Ingo Stammberger, Marc Stadler, Marc P. Hübner, Stefan Kehraus, Achim Hoerauf, Karl G. Wagner
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Pharmaceutics
Subjects:
toxicology
mesoporous silica
poorly soluble drugs
corallopyronin A
preclinical studies
vehicle
Online Access:https://www.mdpi.com/1999-4923/16/3/386

Internet

https://www.mdpi.com/1999-4923/16/3/386

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