Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations
Toxicological studies are a part of the drug development process and the preclinical stages, for which suitable vehicles ensuring easy and safe administration are crucial. However, poor aqueous solubility of drugs complicates vehicle screening for oral administration since non-aqueous solvents are o...
Main Authors: | Tim Becker, Jan Heitkötter, Anna K. Krome, Andrea Schiefer, Kenneth Pfarr, Alexandra Ehrens, Miriam Grosse, Birthe Sandargo, Ingo Stammberger, Marc Stadler, Marc P. Hübner, Stefan Kehraus, Achim Hoerauf, Karl G. Wagner |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-03-01
|
Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/16/3/386 |
Similar Items
-
In Vitro–In Vivo Relationship in Mini-Scale—Enabling Formulations of Corallopyronin A
by: Tim Becker, et al.
Published: (2022-08-01) -
The RNA Polymerase Inhibitor Corallopyronin A Has a Lower Frequency of Resistance Than Rifampicin in <i>Staphylococcus aureus</i>
by: Jan Balansky, et al.
Published: (2022-07-01) -
Elaborations on Corallopyronin A as a Novel Treatment Strategy Against Genital Chlamydial Infections
by: Nathalie Loeper, et al.
Published: (2019-05-01) -
Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A
by: Anna K. Krome, et al.
Published: (2020-11-01) -
Potent In Vitro and Ex Vivo Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A
by: Jennifer L. Edwards, et al.
Published: (2022-10-01)