GLUT4 localisation with the plasma membrane is unaffected by an increase in plasma free fatty acid availability

Abstract Background Insulin-stimulated glucose uptake into skeletal muscle occurs via translocation of GLUT4 from intracellular storage vesicles to the plasma membrane. Elevated free fatty acid (FFA) availability via a lipid infusion reduces glucose disposal, but this occurs in the absence of impair...

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Main Authors: J. S. Barrett, J. A. Strauss, L. S. Chow, S. O. Shepherd, A. J. M. Wagenmakers, Y. Wang
Format: Article
Jezik:English
Izdano: BMC 2024-04-01
Serija:Lipids in Health and Disease
Teme:
Online dostop:https://doi.org/10.1186/s12944-024-02079-z