GLUT4 localisation with the plasma membrane is unaffected by an increase in plasma free fatty acid availability

GLUT4 localisation with the plasma membrane is unaffected by an increase in plasma free fatty acid availability

Abstract Background Insulin-stimulated glucose uptake into skeletal muscle occurs via translocation of GLUT4 from intracellular storage vesicles to the plasma membrane. Elevated free fatty acid (FFA) availability via a lipid infusion reduces glucose disposal, but this occurs in the absence of impair...

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Bibliographic Details
Main Authors: J. S. Barrett, J. A. Strauss, L. S. Chow, S. O. Shepherd, A. J. M. Wagenmakers, Y. Wang
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Lipids in Health and Disease
Subjects:
Lipid infusion
GLUT4 translocation
Skeletal muscle
Online Access:https://doi.org/10.1186/s12944-024-02079-z

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