CDC27-ODC1 Axis Promotes Metastasis, Accelerates Ferroptosis and Predicts Poor Prognosis in Neuroblastoma

CDC27-ODC1 Axis Promotes Metastasis, Accelerates Ferroptosis and Predicts Poor Prognosis in Neuroblastoma

Neuroblastoma (NB) is a devastating malignancy threatening children’s health, and amplification of MYCN is associated with treatment failure and a poor outcome. Here, we aimed to demonstrate the role of cell division cycle 27 (CDC27), an important core subunit of the anaphase-promoting complex, and...

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Bibliographic Details
Main Authors: Lin Qiu, Rui Zhou, Ziyan Luo, Jiangxue Wu, Hua Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Oncology
Subjects:
CDC27
ODC1
neuroblastoma
metastasis
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.774458/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.774458/full

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