NUP98 oncofusions in myeloid malignancies: An update on molecular mechanisms and therapeutic opportunities
Abstract Acute myeloid leukemia (AML) is an aggressive hematological malignancy with a heterogeneous molecular landscape. In the pediatric context, the NUP98 gene is a frequent target of chromosomal rearrangements that are linked to poor prognosis and unfavorable treatment outcomes in different AML...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-09-01
|
| Series: | HemaSphere |
| Online Access: | https://doi.org/10.1002/hem3.70013 |