Development of polymeric micelles loaded with STAT3 inhibitory, Stattic, for cancer treatment

Background. STAT3 is an oncogenic signaling pathway found constitutively active in many types of human malignancies and plays a key role in cancer progression. Stattic is a small molecule, which selectively inhibits the SH2 domain of STAT3. In most studies, stattic has been proposed as a promising s...

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Bibliographic Details
Main Authors: Hamed Masoumzadeh, Nasrin Hoseinzad, Sevda Jafari, Ali Shayanfar, Haleh Vaez, Ommoleila Molavi
Format: Article
Language:fas
Published: Tabriz University of Medical Sciences 2021-10-01
Series:مجله پزشکی دانشگاه علوم پزشکی تبریز
Subjects:
Online Access:https://mj.tbzmed.ac.ir/PDF/mj-43-335.pdf