On-line Electrochemical Tagging of Free Cysteines in Peptides during Nanospray Ionisation Mass Spectrometry: An Overview

On-line Electrochemical Tagging of Free Cysteines in Peptides during Nanospray Ionisation Mass Spectrometry: An Overview

A recently developed nanospray interface for mass spectrometry (MS) was used to electro-generate benzoquinone from hydroquinone. When spraying biomolecules containing free cysteine residues in the presence of hydroquinone, the thiol cysteine moiety reacts via a 1,4-Michael addition with be...

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Bibliographic Details
Main Authors: Loïc Dayon, Christophe Roussel, Hubert H. Girault
Format: Article
Language:deu
Published: Swiss Chemical Society 2004-04-01
Series:CHIMIA
Subjects:
Cyclic voltammetry
Cysteine
Labelling
Mass spectrometry
Quinone
Online Access:https://chimia.ch/chimia/article/view/3832

Internet

https://chimia.ch/chimia/article/view/3832

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