MAPKAPK2, a potential dynamic network biomarker of α-synuclein prior to its aggregation in PD patients

Abstract One of the important pathological features of Parkinson’s disease (PD) is the pathological aggregation of α-synuclein (α-Syn) in the substantia nigra. Preventing the aggregation of α-Syn has become a potential strategy for treating PD. However, the molecular mechanism of α-Syn aggregation i...

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Bibliographic Details
Main Authors: Zhenggang Zhong, Jiabao Li, Jiayuan Zhong, Yilin Huang, Jiaqi Hu, Piao Zhang, Baowen Zhang, Yabin Jin, Wei Luo, Rui Liu, Yuhu Zhang, Fei Ling
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00479-z