A radiolabeled drug tracing method to study neurotrophin-3 retention and distribution in the cochlea after nano-based local delivery

A radiolabeled drug tracing method to study neurotrophin-3 retention and distribution in the cochlea after nano-based local delivery

Hearing loss is the most common sensory deficit worldwide with no approved therapeutics for treatment. Local neurotrophin delivery into the cochlea has shown great potential in protecting and repairing the sensory cells important for hearing. However, delivery of these factors into the inner ear at...

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Bibliographic Details
Main Authors: Patrick Lam, Niliksha Gunewardene, Yutian Ma, Frank Caruso, Trung Nguyen, Brianna Flynn, Andrew K. Wise, Rachael T. Richardson
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:MethodsX
Subjects:
Drug delivery
Nanoparticles
Neurotrophins
Hearing loss
Inner ear
Cochlea
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016120302983

Internet

http://www.sciencedirect.com/science/article/pii/S2215016120302983

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