Rta is the principal activator of Epstein-Barr virus epithelial lytic transcription.

The transition from latent Epstein-Barr virus (EBV) infection to lytic viral replication is mediated by the viral transcription factors Rta and Zta. Although both are required for virion production, dissecting the specific roles played by Rta and Zta is challenging because they induce each other...

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Bibliographic Details
Main Authors: Ahmed Ali, Makoto Ohashi, Alejandro Casco, Reza Djavadian, Mark Eichelberg, Shannon C Kenney, Eric Johannsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010886