Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor

Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor

Androgenetic alopecia (AGA) is the most common type of hair loss, and is mainly caused by the biological effects of testosterone on dermal papilla cells (DPCs). In vitro culturing of DPCs might be a useful tool for the screening of target molecule of AGA. However, primary DPCs cannot continuously pr...

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Bibliographic Details
Main Authors: Tomokazu Fukuda, Kouhei Takahashi, Shin Takase, Ai Orimoto, Takahiro Eitsuka, Kiyotaka Nakagawa, Tohru Kiyono
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
dihydrotestosterone
dermal papilla cells
immortalization
androgen receptor
nuclear localization
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00157/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00157/full

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