7,8-Dihydroxyflavone protects neurons against oxygen-glucose deprivation induced apoptosis and activates the TrkB/Akt pathway

Background 7,8-dihydroxyflavone (7,8-DHF), a selective agonist of tropomyosin related kinase receptor B (TrkB), is known to exert protective effects in neurodegenerative diseases. However, the role of 7,8-DHF in TrkB signaling after ischemic stroke has remained elusive. Methods In the vitro model of...

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Bibliographic Details
Main Authors: Qinxiang Zhou, Hao Tang, Dingqun Bai, Yuhan Kong
Format: Article
Language:English
Published: PeerJ Inc. 2022-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12886.pdf