PDZ-Containing Proteins Targeted by the ACE2 Receptor

Angiotensin-converting enzyme 2 (ACE2) is a main receptor for SARS-CoV-2 entry to the host cell. Indeed, the first step in viral entry is the binding of the viral trimeric spike (S) protein to ACE2. Abundantly present in human epithelial cells of many organs, ACE2 is also expressed in the human brai...

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Bibliographic Details
Main Authors: Célia Caillet-Saguy, Nicolas Wolff
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/11/2281