Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From Staphylococcus aureus

Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From Staphylococcus aureus

Peptidoglycan (PG) is an essential component of the cell envelope, maintaining bacterial cell shape and protecting it from bursting due to turgor pressure. The monoderm bacterium Staphylococcus aureus has a highly cross-linked PG, with ~90% of peptide stems participating in DD-cross-links and up to...

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Bibliographic Details
Main Authors: Roberto Maya-Martinez, J. Andrew N. Alexander, Christian F. Otten, Isabel Ayala, Daniela Vollmer, Joe Gray, Catherine M. Bougault, Alister Burt, Cédric Laguri, Matthieu Fonvielle, Michel Arthur, Natalie C. J. Strynadka, Waldemar Vollmer, Jean-Pierre Simorre
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
peptidoglycan
NMR
X-ray crystallography
penicillin-binding protein 4
Staphylococcus aureus
cyclic muropeptides
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03223/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03223/full

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