Small-Molecule PROTACs for Cancer Immunotherapy

Small-Molecule PROTACs for Cancer Immunotherapy

Unsatisfactory physicochemical properties of macromolecular drugs seriously hinder their application in tumor immunotherapy. However, these problems can be effectively solved by small-molecule compounds. In the promising field of small-molecule drug development, proteolysis targeting chimera (PROTAC...

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Bibliographic Details
Main Authors: Zefan Liu, Yajun Zhang, Yucheng Xiang, Xin Kang
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
targeted protein degradation
proteolysis targeting chimera
tumor immunotherapy
small molecule inhibitors
tumor microenvironment
Online Access:https://www.mdpi.com/1420-3049/27/17/5439

Internet

https://www.mdpi.com/1420-3049/27/17/5439

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