Self-Organizing Global Gene Expression Regulated through Criticality: Mechanism of the Cell-Fate Change.

BACKGROUND:A fundamental issue in bioscience is to understand the mechanism that underlies the dynamic control of genome-wide expression through the complex temporal-spatial self-organization of the genome to regulate the change in cell fate. We address this issue by elucidating a physically motivat...

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Bibliographic Details
Main Authors: Masa Tsuchiya, Alessandro Giuliani, Midori Hashimoto, Jekaterina Erenpreisa, Kenichi Yoshikawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5173342?pdf=render