Extracellular Alpha-Synuclein: Mechanisms for Glial Cell Internalization and Activation

Alpha-synuclein (α-syn) is a small protein composed of 140 amino acids and belongs to the group of intrinsically disordered proteins. It is a soluble protein that is highly expressed in neurons and expressed at low levels in glial cells. The monomeric protein aggregation process induces the formatio...

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Bibliographic Details
Main Authors: Cecilia Chavarría, Rodrigo Ivagnes, José M. Souza
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/5/655