A network-based method for associating genes with autism spectrum disorder

A network-based method for associating genes with autism spectrum disorder

Autism spectrum disorder (ASD) is a highly heritable complex disease that affects 1% of the population, yet its underlying molecular mechanisms are largely unknown. Here we study the problem of predicting causal genes for ASD by combining genome-scale data with a network propagation approach. We con...

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Bibliographic Details
Main Authors: Neta Zadok, Gil Ast, Roded Sharan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Bioinformatics
Subjects:
autism spectrum disorder (ASD)
network propagation
machine learning
ASD genes
random forest
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2024.1295600/full

Internet

https://www.frontiersin.org/articles/10.3389/fbinf.2024.1295600/full

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