Integrated Machine Learning and Chemoinformatics-Based Screening of Mycotic Compounds against Kinesin Spindle ProteinEg5 for Lung Cancer Therapy

Integrated Machine Learning and Chemoinformatics-Based Screening of Mycotic Compounds against Kinesin Spindle ProteinEg5 for Lung Cancer Therapy

Among the various types of cancer, lung cancer is the second most-diagnosed cancer worldwide. The kinesin spindle protein, Eg5, is a vital protein behind bipolar mitotic spindle establishment and maintenance during mitosis. Eg5 has been reported to contribute to cancer cell migration and angiogenesi...

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Bibliographic Details
Main Authors: Priyanka Maiti, Priyanka Sharma, Mahesha Nand, Indra D. Bhatt, Muthannan Andavar Ramakrishnan, Shalini Mathpal, Tushar Joshi, Ragini Pant, Shafi Mahmud, Jesus Simal-Gandara, Sultan Alshehri, Mohammed M. Ghoneim, Maha Alruwaily, Ahmed Abdullah Al Awadh, Mohammed Merae Alshahrani, Subhash Chandra
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
Eg5
lung cancer
secondary metabolites
fungi
machine learning
molecular docking
Online Access:https://www.mdpi.com/1420-3049/27/5/1639

Internet

https://www.mdpi.com/1420-3049/27/5/1639

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