Natural variation of HIV-1 group M integrase: Implications for a new class of antiretroviral inhibitors
<p>Abstract</p> <p>HIV-1 integrase is the third enzymatic target of antiretroviral (ARV) therapy. However, few data have been published on the distribution of naturally occurring amino acid variation in this enzyme. We therefore characterized the distribution of integrase variants...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-08-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/5/1/74 |