Tick-borne encephalitis virus NS4A ubiquitination antagonizes type I interferon-stimulated STAT1/2 signalling pathway

Tick-borne encephalitis virus NS4A ubiquitination antagonizes type I interferon-stimulated STAT1/2 signalling pathway

ABSTRACTTick-borne encephalitis virus (TBEV) accounts for approximately 10,000 annual cases of severe encephalitis in Europe and Asia and causes encephalitis in humans. In this study, we demonstrate TBEV appears to activate the interferon (IFN)-β dependent on RIG-I/MDA5. Both the IFN-β accumulation...

Full description

Bibliographic Details
Main Authors: Qi Yang, Jia You, Yuan Zhou, Yun Wang, Rongjuan Pei, Xinwen Chen, Min Yang, Jizheng Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Tick-borne encephalitis virus (TBEV)
NS4A
ubiquitination
STAT1
STAT2
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1745094

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2020.1745094

Similar Items