Increased production of IL-4 and IL-12p40 from bronchoalveolar lavage cells are biomarkers of Mycobacterium tuberculosis in the sputum.

Increased production of IL-4 and IL-12p40 from bronchoalveolar lavage cells are biomarkers of Mycobacterium tuberculosis in the sputum.

Tuberculosis (TB) causes 1.45 million deaths annually world wide, the majority of which occur in the developing world. Active TB disease represents immune failure to control latent infection from airborne spread. Acid-fast bacillus (AFB) seen on sputum smear is a biomarker for contagiousness.We enro...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Anna Nolan, Elaine Fajardo, Maryann L Huie, Rany Condos, Anil Pooran, Rodney Dawson, Keertan Dheda, Eric Bateman, William N Rom, Michael D Weiden
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC3603887?pdf=render

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