Adeno-Associated Virus as an Effective Malaria Booster Vaccine Following Adenovirus Priming

Adeno-Associated Virus as an Effective Malaria Booster Vaccine Following Adenovirus Priming

An ideal malaria vaccine platform should potently induce protective immune responses and block parasite transmission from mosquito to human, and it should maintain these effects for an extended period. Here, we have focused on vaccine development based on adeno-associated virus serotype 1 (AAV1), a...

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Bibliographic Details
Main Authors: Yenni Yusuf, Tatsuya Yoshii, Mitsuhiro Iyori, Kunitaka Yoshida, Hiroaki Mizukami, Shinya Fukumoto, Daisuke S. Yamamoto, Asrar Alam, Talha Bin Emran, Fitri Amelia, Ashekul Islam, Hiromu Otsuka, Eizo Takashima, Takafumi Tsuboi, Shigeto Yoshida
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
Plasmodium falciparum circumsporozoite protein
Pfs25
human adenovirus serotype 5
adeno-associated virus
malaria vaccine
transmission-blocking
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00730/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00730/full

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