APE1 promotes radiation resistance against radiation-induced pyroptosis by inhibiting the STING pathway in lung adenocarcinoma

APE1 promotes radiation resistance against radiation-induced pyroptosis by inhibiting the STING pathway in lung adenocarcinoma

Mammalian apurinic/apyrimidinic endonuclease 1 (APE1, APEX1) is a multifunctional enzyme that maintains cellular homeostasis. It is involved in the base excision repair (BER) pathway and plays a key role in radiation-induced DNA damage response. However, the relationship between APE1-driven radiatio...

Full description

Bibliographic Details
Main Authors: Jing Zhou, Zixin Wei, Chuan Yang, Dexin Jia, Bo Pan, Yuan Zeng, Di Sun, Yan Yu
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Translational Oncology
Subjects:
Radiosensitivity
LUAD
APE1
STING
Pyroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323001353

Internet

http://www.sciencedirect.com/science/article/pii/S1936523323001353

Similar Items