Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila.
The differentiation efficiency of adult stem cells undergoes a significant decline in aged animals, which is closely related to the decline in organ function and age-associated diseases. However, the underlying mechanisms that ultimately lead to this observed decline of the differentiation efficienc...
Κύριοι συγγραφείς: | , , , , , , , , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Public Library of Science (PLoS)
2021-07-01
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Σειρά: | PLoS Genetics |
Διαθέσιμο Online: | https://doi.org/10.1371/journal.pgen.1009649 |