Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila.

The differentiation efficiency of adult stem cells undergoes a significant decline in aged animals, which is closely related to the decline in organ function and age-associated diseases. However, the underlying mechanisms that ultimately lead to this observed decline of the differentiation efficienc...

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Main Authors: Kun Wu, Yiming Tang, Qiaoqiao Zhang, Zhangpeng Zhuo, Xiao Sheng, Jingping Huang, Jie'er Ye, Xiaorong Li, Zhiming Liu, Haiyang Chen
格式: 文件
语言:English
出版: Public Library of Science (PLoS) 2021-07-01
丛编:PLoS Genetics
在线阅读:https://doi.org/10.1371/journal.pgen.1009649