GSTP1 c.313A > G mutation is an independent risk factor for neutropenia hematotoxicity induced by anthracycline-/paclitaxel-based chemotherapy in breast cancer patients

Abstract Background The link between glutathione S-transferase P1 (GSTP1) c.313A > G polymorphism and chemotherapy-related adverse events remains controversial. The goal of this study was to assess how this variant affected the toxicity of anthracycline-/paclitaxel-based chemotherapy in patients...

Full description

Bibliographic Details
Main Authors: Juanzi Zeng, Heming Wu, Donghua Liu, Liang Li, Jiaquan Li, Qiuming Wang, Min Ye, Qingyan Huang, Zhikang Yu, Jinfeng Zhang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:World Journal of Surgical Oncology
Subjects:
Online Access:https://doi.org/10.1186/s12957-022-02679-y