Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells

Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells

Abstract Background Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a new candidate growth factor for dopaminergic neurons against endoplasmic reticulum stress (ER stress). HSP70 family, a chaperon like heat shock protein family, was proved to be involved in the MANF induced survival p...

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Bibliographic Details
Main Authors: Hui Sun, Ming Jiang, Xing Fu, Qiong Cai, Jingxing Zhang, Yanxin Yin, Jia Guo, Lihua Yu, Yun Jiang, Yigang Liu, Liang Feng, Zhiyu Nie, Jianmin Fang, Lingjing Jin
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Translational Neurodegeneration
Subjects:
HSP70
MANF
Parkinson’s disease
SHSY-5Y cell
Online Access:http://link.springer.com/article/10.1186/s40035-017-0082-8

Internet

http://link.springer.com/article/10.1186/s40035-017-0082-8

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