α7 Nicotinic Acetylcholine Receptors May Improve Schwann Cell Regenerating Potential via Metabotropic Signaling Pathways

α7 Nicotinic Acetylcholine Receptors May Improve Schwann Cell Regenerating Potential via Metabotropic Signaling Pathways

Background: Schwann cells (SCs) are glial cells involved in peripheral axon myelination. SCs also play a strategic role after peripheral nerve injury, regulating local inflammation and axon regeneration. Our previous studies demonstrated the presence of cholinergic receptors in SCs. In particular, t...

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Bibliographic Details
Main Authors: Elisabetta Botticelli, Claudia Guerriero, Sergio Fucile, Maria Egle De Stefano, Carlo Matera, Clelia Dallanoce, Marco De Amici, Ada Maria Tata
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
α7 nicotinic receptors
Schwann cells
metabotropic signals
mTORC1
cell migration
Online Access:https://www.mdpi.com/2073-4409/12/11/1494

Internet

https://www.mdpi.com/2073-4409/12/11/1494

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