Experimental phase determination with selenomethionine or mercury-derivatization in serial femtosecond crystallography

Experimental phase determination with selenomethionine or mercury-derivatization in serial femtosecond crystallography

Serial femtosecond crystallography (SFX) using X-ray free-electron lasers (XFELs) holds enormous potential for the structure determination of proteins for which it is difficult to produce large and high-quality crystals. SFX has been applied to various systems, but rarely to proteins that have previ...

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Bibliographic Details
Main Authors: Keitaro Yamashita, Naoyuki Kuwabara, Takanori Nakane, Tomohiro Murai, Eiichi Mizohata, Michihiro Sugahara, Dongqing Pan, Tetsuya Masuda, Mamoru Suzuki, Tomomi Sato, Atsushi Kodan, Tomohiro Yamaguchi, Eriko Nango, Tomoyuki Tanaka, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Takaki Hatsui, Makina Yabashi, Hiroshi Manya, Tamao Endo, Ryuichi Kato, Toshiya Senda, Hiroaki Kato, So Iwata, Hideo Ago, Masaki Yamamoto, Fumiaki Yumoto, Toru Nakatsu
Format: Article
Language:English
Published: International Union of Crystallography 2017-09-01
Series:IUCrJ
Subjects:
serial femtosecond crystallography
SAD phasing
XFELs
selenomethionine derivatization
mercury soaking
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252517008557

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http://scripts.iucr.org/cgi-bin/paper?S2052252517008557

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