Cutaneous vaccination ameliorates Zika virus-induced neuro-ocular pathology via reduction of anti-ganglioside antibodies

Cutaneous vaccination ameliorates Zika virus-induced neuro-ocular pathology via reduction of anti-ganglioside antibodies

Zika virus (ZIKV) causes moderate to severe neuro-ocular sequelae, with symptoms ranging from conjunctivitis to Guillain-Barré Syndrome (GBS). Despite the international threat ZIKV poses, no licensed vaccine exists. As ZIKV and DENV are closely related, antibodies against one virus have demonstrated...

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Bibliographic Details
Main Authors: Jacob T. Beaver, Lisa K. Mills, Dominika Swieboda, Nadia Lelutiu, Edward S. Esser, Olivia Q. Antao, Eugenia Scountzou, Dahnide T. Williams, Nikolaos Papaioannou, Elizabeth Q. Littauer, Andrey Romanyuk, Richard W. Compans, Mark R. Prausnitz, Ioanna Skountzou
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
zika virus
vaccination
neuro-pathology
auto-immunity
Online Access:http://dx.doi.org/10.1080/21645515.2020.1775460

Internet

http://dx.doi.org/10.1080/21645515.2020.1775460

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