Elevated Plasma Concentration of 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR) Highlights Malignancy of Renal Cell Carcinoma

Elevated Plasma Concentration of 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR) Highlights Malignancy of Renal Cell Carcinoma

Nicotinamide (NA) derivatives play crucial roles in various biological processes, such as inflammation, regulation of the cell cycle, and DNA repair. Recently, we proposed that 4-pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR), an unusual derivative of NA, could be classified as an oncometabolite...

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Bibliographic Details
Main Authors: Agata Jedrzejewska, Patrycja Jablonska, Teresa Gawlik-Jakubczak, Mateusz Czajkowski, Patrycja Maszka, Paulina Mierzejewska, Ryszard T. Smolenski, Ewa M. Slominska
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
renal cell carcinoma
nicotinamide metabolism
4-pyridone-3-carboxamide-1-β-D-ribonucleoside
prognosis
histopathological subtypes
Online Access:https://www.mdpi.com/1422-0067/25/4/2359

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https://www.mdpi.com/1422-0067/25/4/2359

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