Benzochromenopyrimidines: Synthesis, Antiproliferative Activity against Colorectal Cancer and Physicochemical Properties

Ten new differently substituted 3-benzyl-5-aryl-3,5-dihydro-4<i>H</i>-benzo[6,7]chromeno[2,3-<i>d</i>]pyrimidin-4,6,11-triones <b>3</b> were synthesized by a simple and cost-efficient procedure in a one-pot, three-component reaction from readily available ethyl 2-...

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Bibliographic Details
Main Authors: Emna Choura, Fares Elghali, Paul J. Bernard, Dhouha Msalbi, José Marco-Contelles, Sami Aifa, Lhassane Ismaili, Fakher Chabchoub
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/22/7878