Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.

Mechanistic target of rapamycin (Mtor) is required for embryonic inner cell mass proliferation during early development. However, Mtor expression levels are very low in the mouse heart during embryogenesis. To determine if Mtor plays a role during mouse cardiac development, cardiomyocyte specific Mt...

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Bibliographic Details
Main Authors: Yi Zhu, Karla M P Pires, Kevin J Whitehead, Curtis D Olsen, Benjamin Wayment, Yi Cheng Zhang, Heiko Bugger, Olesya Ilkun, Sheldon E Litwin, George Thomas, Sara C Kozma, E Dale Abel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544830?pdf=render