Ligustrazine alleviates pulmonary arterial hypertension in rats by promoting the formation of myocardin transcription complex in the nucleus of pulmonary artery smooth muscle cells

Abstract Pulmonary arterial hypertension (PAH) is a pathophysiological state of abnormally elevated pulmonary arterial pressure caused by drugs, inflammation, toxins, viruses, hypoxia, and other risk factors. We studied the therapeutic effect and target of tetramethylpyrazine (tetramethylpyrazine [T...

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Bibliographic Details
Main Authors: Xichao Yu, Mingjie Wu, Qinhai Meng, Weijie Zhu, Chenyan Zhang, Bowen Liu, Yuewen Qi, Shuqun Gu, Xinyu Wang, Jingli Wen, Yu Li, Xu Qi
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13534