Functional role of WW domain‐containing proteins in tumor biology and diseases: Insight into the role in ubiquitin‐proteasome system

Functional role of WW domain‐containing proteins in tumor biology and diseases: Insight into the role in ubiquitin‐proteasome system

Abstract The ubiquitin‐proteasome system (UPS) governs the protein degradation process and balances proteostasis and cellular homeostasis. It is a well‐controlled mechanism, in which removal of the damaged or excessive proteins is essential in driving signal pathways for cell survival or death. Accu...

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Bibliographic Details
Main Authors: Shenq‐Shyang Huang, Li‐Jin Hsu, Nan‐Shan Chang
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:FASEB BioAdvances
Subjects:
degradation
neural diseases
proteasome
tumorigenesis
ubiquitination
WW domain
Online Access:https://doi.org/10.1096/fba.2019-00060

Internet

https://doi.org/10.1096/fba.2019-00060

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