The molecular effect of a polymorphic microRNA binding site of Wolfram syndrome 1 gene in dogs

Abstract Background Although the molecular function of wolframin remains unclear, the lack of this protein is known to cause stress in the endoplasmic reticulum. Some variants in the Wolfram Syndrome 1 gene (WFS1) were associated with various neuropsychiatric disorders in humans, such as aggressiven...

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Bibliographic Details
Main Authors: Dora Koller, Eniko Kubinyi, Zsuzsanna Elek, Helga Nemeth, Adam Miklosi, Maria Sasvari-Szekely, Zsolt Ronai
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Genetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12863-020-00879-7