The molecular effect of a polymorphic microRNA binding site of Wolfram syndrome 1 gene in dogs
Abstract Background Although the molecular function of wolframin remains unclear, the lack of this protein is known to cause stress in the endoplasmic reticulum. Some variants in the Wolfram Syndrome 1 gene (WFS1) were associated with various neuropsychiatric disorders in humans, such as aggressiven...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
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Series: | BMC Genetics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12863-020-00879-7 |