A New Bayesian Methodology for Nonlinear Model Calibration in Computational Systems Biology
Computational modeling is a common tool to quantitatively describe biological processes. However, most model parameters are usually unknown because they cannot be directly measured. Therefore, a key issue in Systems Biology is model calibration, i.e., estimate parameters from experimental data. Exis...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-07-01
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Series: | Frontiers in Applied Mathematics and Statistics |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fams.2020.00025/full |