Mild hypothermia combined with dexmedetomidine reduced brain, lung, and kidney damage in experimental acute focal ischemic stroke

Mild hypothermia combined with dexmedetomidine reduced brain, lung, and kidney damage in experimental acute focal ischemic stroke

Abstract Background Sedatives and mild hypothermia alone may yield neuroprotective effects in acute ischemic stroke (AIS). However, the impact of this combination is still under investigation. We compared the effects of the combination of mild hypothermia or normothermia with propofol or dexmedetomi...

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Bibliographic Details
Main Authors: Denise Battaglini, Adriana Lopes da Silva, Nathane Santanna Felix, Gisele Rodrigues, Mariana Alves Antunes, Nazareth Novaes Rocha, Vera Luiza Capelozzi, Marcelo Marcos Morales, Fernanda Ferreira Cruz, Chiara Robba, Pedro Leme Silva, Paolo Pelosi, Patricia Rieken Macedo Rocco
Format: Article
Language:English
Published: SpringerOpen 2022-12-01
Series:Intensive Care Medicine Experimental
Subjects:
Neuroprotection
Hypothermia
Ischemic stroke
Animal model
Kidney
Online Access:https://doi.org/10.1186/s40635-022-00481-4

Internet

https://doi.org/10.1186/s40635-022-00481-4

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