Establishment and Evaluation of a Parametric Population Pharmacokinetic Model Repository for Ganciclovir and Valganciclovir

Establishment and Evaluation of a Parametric Population Pharmacokinetic Model Repository for Ganciclovir and Valganciclovir

Background: Ganciclovir and valganciclovir are used for prophylaxis and treatment of cytomegalovirus infection. However, there is great interindividual variability in ganciclovir’s pharmacokinetics (PK), highlighting the importance of individualized dosing. To facilitate model-informed precision dos...

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Bibliographic Details
Main Authors: Wenyu Yang, Wenyao Mak, Amanda Gwee, Meng Gu, Yue Wu, Yufei Shi, Qingfeng He, Xiaoqiang Xiang, Bing Han, Xiao Zhu
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceutics
Subjects:
ganciclovir
valganciclovir
population pharmacokinetics
model-informed precision dosing
model repository
Online Access:https://www.mdpi.com/1999-4923/15/7/1801

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https://www.mdpi.com/1999-4923/15/7/1801

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