Injured adult retinal axons with Pten and Socs3 co-deletion reform active synapses with suprachiasmatic neurons

Injured adult retinal axons with Pten and Socs3 co-deletion reform active synapses with suprachiasmatic neurons

Despite advances in promoting axonal regeneration after adult central nervous system injury, elicitation of a large number of lesion-passing axons reform active synaptic connections with natural target neurons remains limited. By deleting both Pten and Socs3 in retinal ganglion cells, we report that...

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Bibliographic Details
Main Authors: Songshan Li, Qinghai He, Hao Wang, Xuming Tang, Kam Wing Ho, Xin Gao, Qian Zhang, Yang Shen, Annie Cheung, Francis Wong, Yung Hou Wong, Nancy Y. Ip, Liwen Jiang, Wing Ho Yung, Kai Liu
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Neurobiology of Disease
Subjects:
Axon regeneration and rewiring
Intrinsic mechanisms
Pre-chiasm lesion
Retinal ganglion cells
Suprachiasmatic nucleus
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002927

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http://www.sciencedirect.com/science/article/pii/S0969996114002927

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