Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells.

The sympathetic nervous system (SNS) contributes to immune balance by promoting anti-inflammatory B cells. However, whether B cells possess a self-regulating mechanism by which they modulate regulatory B cell (Breg) function is not well understood. In this study, we investigated the ability of B cel...

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Bibliographic Details
Main Authors: Nadine Honke, Torsten Lowin, Birgit Opgenoorth, Namir Shaabani, Alexander Lautwein, John R Teijaro, Matthias Schneider, Georg Pongratz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001513