Application of human iPSC-derived macrophages in a miniaturized high-content-imaging-based efferocytosis assay

Application of human iPSC-derived macrophages in a miniaturized high-content-imaging-based efferocytosis assay

Macrophages play a pivotal role in drug discovery due to their key regulatory functions in health and disease. Overcoming the limited availability and donor variability of human monocyte-derived macrophages (MDMs), human induced pluripotent stem cell (iPSC)-derived macrophages (IDMs) could provide a...

Full description

Bibliographic Details
Main Authors: Sarah Bitzer, Mozhgan Dehghan Harati, Karim C. El Kasmi, Daniela Schloesser, Julia Sauer, Heiko Olbrich, Michael Schuler, Florian Gantner, Ralf Heilker
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:SLAS Discovery
Subjects:
hiPSC-derived macrophages
Upscaling
High-content-imaging
Miniaturization
Efferocytosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2472555223000308

Internet

http://www.sciencedirect.com/science/article/pii/S2472555223000308

Similar Items